Title : Thyrotropin-releasing hormone stimulation of phosphoinositide hydrolysis desensitizes. Evidence against mediation by protein kinase C or calcium.

Pub. Date : 1991 Nov

PMID : 1657582






1 Functional Relationships(s)
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1 Here we show that TRH stimulation of phosphoinositide (PPI) hydrolysis, measured as inositol phosphate accumulation in the presence of LiCl, desensitizes in rat pituitary GH3 cells and in rat glioma C6 cells stably transfected with mouse pituitary TRH receptor complementary DNA. Inositol Phosphates thyrotropin releasing hormone Rattus norvegicus