Title : Transfection and expression of human O6-methylguanine-DNA methyltransferase (MGMT) cDNA in Chinese hamster cells: the role of MGMT in protection against the genotoxic effects of alkylating agents.

Pub. Date : 1991 Oct

PMID : 1657427






1 Functional Relationships(s)
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Protein Name
Organism
1 The high MGMT expressors became strongly resistant to the killing effects of MNNG, HeCNU, N-methyl-N-nitrosourea (MNU) and, to a significant lesser degree, methyl methanesulfonate (MMS) and ethyl methanesulfonate (EMS). Ethyl Methanesulfonate O-6-methylguanine-DNA methyltransferase Homo sapiens