Pub. Date : 1991 May
PMID : 1657241
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | It has previously been shown that administration of cyclosporine causes a prompt (within 15 min after infusion) increase in circulating level of endothelin 1 and a pattern of glomerular hypoperfusion and hypofiltration which can be ameliorated with antiendothelin antibody. | Cyclosporine | endothelin 1 | Rattus norvegicus |
| 2 | We now show that 60 min after cyclosporine, serum endothelin 1 level falls to less than 2.55 +/- 0.31 pg/mL (N = 6), a value comparable to that found in normal animals (less than 2 pg/mL). | Cyclosporine | endothelin 1 | Rattus norvegicus |