Title : SB-649915, a novel, potent 5-HT1A and 5-HT1B autoreceptor antagonist and 5-HT re-uptake inhibitor in native tissue.

Pub. Date : 2006 Apr 24

PMID : 16571351






1 Functional Relationships(s)
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1 It has been proven that selective serotonin re-uptake inhibitors are effective antidepressants but the delay to therapeutic onset of these agents is thought to be due to the time required for 5-HT1A, and possibly 5-HT1B, autoreceptor desensitisation. Serotonin 5-hydroxytryptamine receptor 1B Homo sapiens