Pub. Date : 1991 Jun
PMID : 1656856
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Erythromycin and some other macrolide antibiotics can first induce a cytochrome P-450 isozyme similar to the one induced in rats by pregnenolone-16 alpha-carbonitrile and then inhibit it by forming a stable cytochrome P-450-metabolite complex. | Erythromycin | cytochrome P450, family 2, subfamily g, polypeptide 1 | Rattus norvegicus |
| 2 | Erythromycin and some other macrolide antibiotics can first induce a cytochrome P-450 isozyme similar to the one induced in rats by pregnenolone-16 alpha-carbonitrile and then inhibit it by forming a stable cytochrome P-450-metabolite complex. | Erythromycin | cytochrome P450, family 2, subfamily g, polypeptide 1 | Rattus norvegicus |
| 3 | Approximately 40% of cytochrome P-450 was complexed with erythromycin metabolite. | Erythromycin | cytochrome P450, family 2, subfamily g, polypeptide 1 | Rattus norvegicus |