Title : Gefitinib and the modulation of the signaling pathways downstream of epidermal growth factor receptor in human liver cancer cells.

Pub. Date : 2006 Feb

PMID : 16568376






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 When the cells were co-treated with gefitinib and TGF-alpha, enhanced proliferation and activation of ERK1/2 and AKT were canceled, and the cell-cycle promotion by TGF-alpha was inhibited by co-treatment with gefitinib and TGF-alpha, independently of expression levels of EGFR. Gefitinib mitogen-activated protein kinase 3 Homo sapiens
2 When the cells were co-treated with gefitinib and TGF-alpha, enhanced proliferation and activation of ERK1/2 and AKT were canceled, and the cell-cycle promotion by TGF-alpha was inhibited by co-treatment with gefitinib and TGF-alpha, independently of expression levels of EGFR. Gefitinib mitogen-activated protein kinase 3 Homo sapiens