Title : Hippocampal upregulation of the cyclooxygenase-2 gene following neonatal clomipramine treatment (a model of depression).

Pub. Date : 2006 Nov-Dec

PMID : 16568149






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Rats injected neonatally with clomipramine showed depressive-like symptoms in adulthood, as well as decreased levels of the brain-derived neurotrophic factor (BDNF) and a quantitative differential expression of the COX-2 gene (Real Time PCR) and protein (immunohistochemistry) in the hippocampus. Clomipramine cytochrome c oxidase II, mitochondrial Rattus norvegicus