Pub. Date : 1991 Sep 1
PMID : 1654885
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The most pronounced effects on VIP binding were obtained with tunicamycin and deoxymannojirimycin, which respectively caused 80% and 67% inhibition. | Tunicamycin | vasoactive intestinal peptide | Homo sapiens |
| 2 | In contrast, tunicamycin and castanospermine caused decreases in the cell-surface number of functional VIP receptors without affecting affinity. | Tunicamycin | vasoactive intestinal peptide | Homo sapiens |
| 3 | When compared with their counterpart synthesized in control cells, VIP-binding proteins produced by deoxymannojirimycin- or swainsonine-treated cells were smaller in size and exhibited the expected sensitivity to Endo H. No modification in the apparent molecular mass was observed in the presence of either castanospermine or tunicamycin. | Tunicamycin | vasoactive intestinal peptide | Homo sapiens |