Pub. Date : 2006 Jul 27
PMID : 16547505
10 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | TCF-4 isoforms absent in TCF-4 mutated MSI-H colorectal cancer cells colocalize with nuclear CtBP and repress TCF-4-mediated transcription. | ctbp | transcription factor 4 | Homo sapiens |
| 2 | TCF-4 isoforms absent in TCF-4 mutated MSI-H colorectal cancer cells colocalize with nuclear CtBP and repress TCF-4-mediated transcription. | ctbp | transcription factor 4 | Homo sapiens |
| 3 | TCF-4 isoforms absent in TCF-4 mutated MSI-H colorectal cancer cells colocalize with nuclear CtBP and repress TCF-4-mediated transcription. | ctbp | transcription factor 4 | Homo sapiens |
| 4 | Of interest, we described a frequent TCF-4 frameshift mutation in mismatch-repair deficient colorectal cancers (MSI-H cancers) that leads to the selective loss of TCF-4 isoforms with CtBP binding abilities. | ctbp | transcription factor 4 | Homo sapiens |
| 5 | Of interest, we described a frequent TCF-4 frameshift mutation in mismatch-repair deficient colorectal cancers (MSI-H cancers) that leads to the selective loss of TCF-4 isoforms with CtBP binding abilities. | ctbp | transcription factor 4 | Homo sapiens |
| 6 | We provide here data that argue for a partial colocalization of CtBP with TCF-4 isoforms containing CtBP binding domains in cellulo, and for a functional role of CtBP in repressing TCF-4 mediated transcription. | ctbp | transcription factor 4 | Homo sapiens |
| 7 | We provide here data that argue for a partial colocalization of CtBP with TCF-4 isoforms containing CtBP binding domains in cellulo, and for a functional role of CtBP in repressing TCF-4 mediated transcription. | ctbp | transcription factor 4 | Homo sapiens |
| 8 | We provide here data that argue for a partial colocalization of CtBP with TCF-4 isoforms containing CtBP binding domains in cellulo, and for a functional role of CtBP in repressing TCF-4 mediated transcription. | ctbp | transcription factor 4 | Homo sapiens |
| 9 | Taken together, our results strongly suggest that CtBP would play a role in regulating TCF-4 mediated transcription upon its binding with some TCF-4 isoforms encoded by alternatively spliced mRNA. | ctbp | transcription factor 4 | Homo sapiens |
| 10 | Taken together, our results strongly suggest that CtBP would play a role in regulating TCF-4 mediated transcription upon its binding with some TCF-4 isoforms encoded by alternatively spliced mRNA. | ctbp | transcription factor 4 | Homo sapiens |