Title : Inhibition of the phosphatidylinositol 3-kinase/Akt pathway sensitizes MDA-MB468 human breast cancer cells to cerulenin-induced apoptosis.

Pub. Date : 2006 Mar

PMID : 16546963






1 Functional Relationships(s)
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1 In MDA-MB468 cells, cerulenin- and LY294002-mediated apoptosis was associated with caspase-3 activation and the release of cytochrome c from mitochondria to cytosol. Cerulenin caspase 3 Homo sapiens