Title : Pharmacological characterization in vitro of EP2306 and EP2302, potent inhibitors of squalene synthase and lipid biosynthesis.

Pub. Date : 2006 Mar 27

PMID : 16545796






1 Functional Relationships(s)
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1 Furthermore, both EP2300 compounds and simvastatin significantly reduced triglyceride synthesis and apoB secretion and increased LDL receptor expression and LDL uptake in HepG2 cells. Simvastatin apolipoprotein B Homo sapiens