Title : ATP-induced apoptotic cell death in porcine ovarian theca cells through P2X7 receptor activation.

Pub. Date : 2006 Jun

PMID : 16541451






1 Functional Relationships(s)
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1 Isolated porcine theca cells maintained in primary cultures and tested with 1 mM ATP or 250 microM Bz-ATP, a specific agonist of P2X7, responded with an increase in intracellular calcium concentration, as demonstrated in cells loaded with fluo-4 as calcium indicator. 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate purinergic receptor P2X, ligand-gated ion channel, 7 Mus musculus