Title : Evidence that GAD65 mediates increased GABA synthesis during intense neuronal activity in vivo.

Pub. Date : 2006 Apr

PMID : 16539672






3 Functional Relationships(s)
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1 Evidence that GAD65 mediates increased GABA synthesis during intense neuronal activity in vivo. gamma-Aminobutyric Acid glutamate decarboxylase 2 Rattus norvegicus
2 In this study we tested the hypothesis that the 65-kDa isoform of glutamate decarboxylase (GAD(65)) mediates activity-dependent GABA synthesis as invoked by seizures in anesthetized rats. gamma-Aminobutyric Acid glutamate decarboxylase 2 Rattus norvegicus
3 Our results are consistent with a major role for GAD(65) in activity-dependent GABA synthesis. gamma-Aminobutyric Acid glutamate decarboxylase 2 Rattus norvegicus