Pub. Date : 2006 Mar 21
PMID : 16537427
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here, we report that the proapoptotic Bcl-2 family member Bid is required for the development of pulmonary fibrosis after the intratracheal instillation of bleomycin. | Bleomycin | BH3 interacting domain death agonist | Mus musculus |
| 2 | Mice lacking Bid exhibited significantly less pulmonary fibrosis in response to bleomycin compared with WT mice. | Bleomycin | BH3 interacting domain death agonist | Mus musculus |
| 3 | Bleomycin induced similar levels cell death in vitro in alveolar epithelial cells isolated from WT and bid(-/-) mice. | Bleomycin | BH3 interacting domain death agonist | Mus musculus |