Title : N-3 PUFAs reduce oxidative stress in ESRD patients on maintenance HD by inhibiting 5-lipoxygenase activity.

Pub. Date : 2006 Apr

PMID : 16531984






1 Functional Relationships(s)
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1 Reactive oxygen species formation and release of pro-inflammatory/pro-atherogenic cytokines, that is, interleukin 1-beta and tumor necrosis factor-alpha, need the activation of the arachidonic acid cascade via the enzyme 5-lipoxygenase (5-Lox). Arachidonic Acid interleukin 1 beta Homo sapiens