Title : Global alterations in mRNA polysomal recruitment in a cell model of colorectal cancer progression to metastasis.

Pub. Date : 2006 Jul

PMID : 16531451






1 Functional Relationships(s)
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1 Looking for an upstream determinant of translational deregulation, we found an increase in the hyperphosphorylated form of the 4E-BP1 protein in the metastatic cell line, possibly resulting in an increased activation of cap-dependent translation due to increased activity of the eIF4E protein. cap eukaryotic translation initiation factor 4E Homo sapiens