Title : Effect of valdecoxib pretreatment on pain and secondary hyperalgesia: a randomized controlled trial in healthy volunteers [ISRCTN05282752, NCT00260325].

Pub. Date : 2006 Mar 10

PMID : 16529650






1 Functional Relationships(s)
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1 This study aimed to investigate the efficacy of a single, oral dose of the specific COX-2 inhibitor-valdecoxib in attenuating the central sensitization - induced secondary hyperalgesia in a heat/capsaicin pain model in healthy volunteers. valdecoxib mitochondrially encoded cytochrome c oxidase II Homo sapiens