Title : Cyclooxygenase inhibitory natural products: current status.

Pub. Date : 2006

PMID : 16529558






4 Functional Relationships(s)
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1 Recent reports evidence that selective COX-2 inhibitor such as rofecoxib, can lead to thrombotic cardiovascular events through inhibition of prostacyclin formation in the infracted heart. rofecoxib mitochondrially encoded cytochrome c oxidase II Homo sapiens
2 Moreover, the COX-2/COX-1 selectivity ratio is vital in the design of COX-2 inhibitory drugs, as it is clear from rofecoxib, which is more than 50-fold COX-2 selective. rofecoxib mitochondrially encoded cytochrome c oxidase II Homo sapiens
3 Moreover, the COX-2/COX-1 selectivity ratio is vital in the design of COX-2 inhibitory drugs, as it is clear from rofecoxib, which is more than 50-fold COX-2 selective. rofecoxib mitochondrially encoded cytochrome c oxidase II Homo sapiens
4 Moreover, the COX-2/COX-1 selectivity ratio is vital in the design of COX-2 inhibitory drugs, as it is clear from rofecoxib, which is more than 50-fold COX-2 selective. rofecoxib mitochondrially encoded cytochrome c oxidase II Homo sapiens