Pub. Date : 2006 Mar 8
PMID : 16525063
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Deletion of CREB (crh-1) or loss of one copy of CBP (cbp-1) enhanced polyglutamine toxicity in C. elegans neurons. | polyglutamine | Protein cbp-1 | Caenorhabditis elegans |
| 2 | Deletion of CREB (crh-1) or loss of one copy of CBP (cbp-1) enhanced polyglutamine toxicity in C. elegans neurons. | polyglutamine | Protein cbp-1 | Caenorhabditis elegans |
| 3 | Our results suggest that polyglutamine expansions perturb transcription of CREB/CBP targets and that specific targeting of HDACs will be useful in reducing associated neurodegeneration. | polyglutamine | Protein cbp-1 | Caenorhabditis elegans |