Title : Promotion of prostatic metastatic migration towards human bone marrow stoma by Omega 6 and its inhibition by Omega 3 PUFAs.

Pub. Date : 2006 Mar 27

PMID : 16523199






1 Functional Relationships(s)
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1 This observed invasion is mediated by the arachidonic acid metabolite prostaglandin E2 and is inhibited by the Omega-3 poly-unsaturated fatty acids eicosapentaenoic acid and docosahexaenoic acid at a ratio of 1 : 2 Omega-3 : Omega-6, and by the COX-2 inhibitor NS-398. Eicosapentaenoic Acid mitochondrially encoded cytochrome c oxidase II Homo sapiens