Title : Impairment of PAR-2-mediated relaxation system in colonic smooth muscle after intestinal inflammation.

Pub. Date : 2006 May

PMID : 16520739






1 Functional Relationships(s)
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1 Stimulation of PAR-2 by trypsin-induced relaxation of carbachol- and KCl-induced contractions in normal rat colonic smooth muscle was completely resolved by tissue pretreatment with apamin, but not by pretreatment with l-NMMA or a cocktail of neuronal blockers (tetrodotoxin, hexamethonium and propranolol). Propranolol F2R like trypsin receptor 1 Rattus norvegicus