Pub. Date : 2006 Jun
PMID : 16516965
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Neuropeptide Y mRNA expression levels following chronic olanzapine, clozapine and haloperidol administration in rats. | Haloperidol | neuropeptide Y | Rattus norvegicus |
| 2 | Using quantitative in situ hybridization, this study examined regional changes in rat brain mRNA levels encoding neuropeptide Y (NPY) following olanzapine, clozapine and haloperidol administration (1.2, 1.5 and 2.0 mg/kg, oral) for 36 days. | Haloperidol | neuropeptide Y | Rattus norvegicus |
| 3 | Haloperidol decreased NPY mRNA expression in the amygdala and hippocampus (-69%, -64%, p<0.05). | Haloperidol | neuropeptide Y | Rattus norvegicus |
| 4 | In the lateral septal nucleus, NPY mRNA levels significantly decreased in the olanzapine group (-66%, p<0.05), a trend toward a decrease was observed in the clozapine group, and no change was found in the haloperidol treated group. | Haloperidol | neuropeptide Y | Rattus norvegicus |