Title : Prostaglandin E potentiates the immunologically stimulated histamine release from human peripheral blood-derived mast cells through EP1/EP3 receptors.

Pub. Date : 2006 Apr

PMID : 16512814






3 Functional Relationships(s)
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1 AIMS: The present study was to characterize pharmacologically the prostanoid receptors by investigating the effects of prostanoid receptor agonists on the immunoglobulin E (IgE)-mediated histamine release from the cultured mast cells. Histamine immunoglobulin heavy constant epsilon Homo sapiens
2 AIMS: The present study was to characterize pharmacologically the prostanoid receptors by investigating the effects of prostanoid receptor agonists on the immunoglobulin E (IgE)-mediated histamine release from the cultured mast cells. Histamine immunoglobulin heavy constant epsilon Homo sapiens
3 CONCLUSIONS: The present results suggest that PGE2 potentiates the IgE-mediated histamine release from the cultured mast cell via EP3 and/or EP1 receptors. Histamine immunoglobulin heavy constant epsilon Homo sapiens