Title : Fall in intracellular pH mediated by GABAA receptors in cultured rat astrocytes.

Pub. Date : 1991 May 13

PMID : 1650936






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In a solution containing 22 mM HCO3-, muscimol produced a reversible, concentration-dependent fall in pHi with a maximum of about 0.1-0.15 units. Bicarbonates glucose-6-phosphate isomerase Rattus norvegicus
2 The muscimol-induced fall in pHi was antagonized by an increase in the external K+ concentration, which suggest that the acidosis is an immediate consequence of a net efflux of HCO3- through GABAA receptor channels rather than an indirect effect caused by a change in membrane potential. Bicarbonates glucose-6-phosphate isomerase Rattus norvegicus