Pub. Date : 1991
PMID : 1650862
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | While ramiprilat itself induced an increase of basal [Ca2+]i, the Ca(2+)-mobilizing effect of angiotensin II (AII) was blunted in the presence of the ACE inhibitor (659 +/- 38 nM vs 360 +/- 45 nM, p less than .001). | ramiprilat | angiotensinogen | Homo sapiens |
| 2 | Ramiprilat-induced contraction of cultured smooth muscle cells may not be relevant in vivo, but the increase of basal [Ca2+]i by ramiprilat may reflect a "reset" of the cellular Ca(2+)-mobilizing mechanism or a depletion of cellular Ca2+ stores and may thus explain the attenuation of the Ca(2+)-mobilizing effect of AII. | ramiprilat | angiotensinogen | Homo sapiens |