Title : Effect of isothiocyanates on nuclear accumulation of NF-kappaB, Nrf2, and thioredoxin in caco-2 cells.

Pub. Date : 2006 Mar 8

PMID : 16506816






1 Functional Relationships(s)
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1 Early effects (only 1 h of exposure) of three isothiocyanates (benzyl, phenylethyl, and sulforaphane) on nuclear accumulation of thioredoxin, APE/Ref-1, and transcription factors NF-kappaB and Nrf2, as well as production of reactive oxygen species (ROS) and reduced glutathione levels were examined in human adenocarcinoma Caco-2 cells. Isothiocyanates apurinic/apyrimidinic endodeoxyribonuclease 1 Homo sapiens