Title : Pathogenesis of nonsteroidal antiinflammatory drug-induced asthma.

Pub. Date : 2006 Feb

PMID : 16505607






1 Functional Relationships(s)
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1 Leukotriene C4 synthase has been established as a key genetic determinant of aspirin-induced asthma, but recent studies have demonstrated that several single nucleotide polymorphisms in the promoters of prostaglandin E2 receptor subtype 2, CYSLTR1 and CYSLTR2 and T-box expressed in T cells (TBX21) could increase risk for the condition. Aspirin leukotriene C4 synthase Homo sapiens