Title : Inhibition of platelet-activating factor biosynthesis by adenosine and histamine in human neutrophils: involvement of cPLA2alpha and reversal by lyso-PAF.

Pub. Date : 2006 May

PMID : 16501051






1 Functional Relationships(s)
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1 In this study, we demonstrate that CGS-21680 (a selective agonist of the adenosine A2A receptor) and histamine also potently inhibit PAF biosynthesis in agonist [formyl Met-Leu-Phe (fMLP)]- and thapsigargin-activated human PMN. N-Formylmethionine Leucyl-Phenylalanine formyl peptide receptor 1 Homo sapiens