Pub. Date : 1991 Aug
PMID : 1649745
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The effect of OCT on osteocalcin secretion and alkaline phosphatase (ALP) activity in ROS 17/2.8 cells was also determined. | maxacalcitol | bone gamma-carboxyglutamate protein | Rattus norvegicus |
| 2 | Pretreatment for 24 h with either 1,25-(OH)2D3 or OCT resulted in a dose-dependent enhancement of osteocalcin secretion. | maxacalcitol | bone gamma-carboxyglutamate protein | Rattus norvegicus |
| 3 | Thus, OCT, like 1,25-(OH)2D3, up-regulates the vitamin D receptor, stimulates osteocalcin secretion, and increases ALP activity in ROS 17/2.8 cells, suggesting that the analog may be as active as 1,25-(OH)2D3 in stimulating bone formation in vivo. | maxacalcitol | bone gamma-carboxyglutamate protein | Rattus norvegicus |