Title : Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix.

Pub. Date : 2006 Feb 27

PMID : 16492808






1 Functional Relationships(s)
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1 In this study, we show that the Rho GTPase Rac1, via a proline stretch in its COOH terminus, binds directly to the SH3 domain of the Cdc42/Rac activator beta-Pix (p21-activated kinase [Pak]-interacting exchange factor). Proline AKT serine/threonine kinase 1 Homo sapiens