Title : Aging of mipafox-inhibited human acetylcholinesterase proceeds by displacement of both isopropylamine groups to yield a phosphate adduct.

Pub. Date : 2006 Feb

PMID : 16485911






3 Functional Relationships(s)
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Protein Name
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1 Aging of mipafox-inhibited human acetylcholinesterase proceeds by displacement of both isopropylamine groups to yield a phosphate adduct. Phosphates acetylcholinesterase (Cartwright blood group) Homo sapiens
2 In contrast, the analogous mass shift for kinetically aged MIP-inhibited AChE was 80.7 +/- 0.9 Da, corresponding to a phosphate adduct. Phosphates acetylcholinesterase (Cartwright blood group) Homo sapiens
3 Further research will be required to elucidate the detailed mechanism of formation of a phosphate conjugate from MIP-inhibited AChE; however, knowledge of the identity of this adduct will be useful in biomarker studies. Phosphates acetylcholinesterase (Cartwright blood group) Homo sapiens