Title : Nuclear receptors and autoimmune disease: the potential of PPAR agonists to treat multiple sclerosis.

Pub. Date : 2006 Mar

PMID : 16484546






2 Functional Relationships(s)
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1 Recently, we examined the role of PPARgamma in EAE and observed that administration of the PPARgamma agonist 15-deoxy-Delta(12,14) prostaglandin J2 exerted a significant therapeutic effect predominantly by inhibiting the activation and expansion of encephalitogenic T cells. 15-deoxy-delta peroxisome proliferator activated receptor gamma Homo sapiens
2 Recently, we examined the role of PPARgamma in EAE and observed that administration of the PPARgamma agonist 15-deoxy-Delta(12,14) prostaglandin J2 exerted a significant therapeutic effect predominantly by inhibiting the activation and expansion of encephalitogenic T cells. 15-deoxy-delta peroxisome proliferator activated receptor gamma Homo sapiens