Title : Inhibition of benzo[a]pyrene-activating enzymes and DNA binding in human bronchial epithelial BEAS-2B cells by methoxylated flavonoids.

Pub. Date : 2006 Aug

PMID : 16484233






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 BaP exposure also increased both CYP1A1/1B1 and microsomal epoxide hydrolase (mEH) enzyme activities with a maximum 10-fold increase at 48 h. BaP induced CYP1A1 protein and mRNA levels maximally after 48 h. In contrast, although CYP1B1 mRNA was rapidly induced, its protein expression showed a very poor response. Benzo(a)pyrene cytochrome P450 family 1 subfamily B member 1 Homo sapiens
2 BaP exposure also increased both CYP1A1/1B1 and microsomal epoxide hydrolase (mEH) enzyme activities with a maximum 10-fold increase at 48 h. BaP induced CYP1A1 protein and mRNA levels maximally after 48 h. In contrast, although CYP1B1 mRNA was rapidly induced, its protein expression showed a very poor response. Benzo(a)pyrene cytochrome P450 family 1 subfamily B member 1 Homo sapiens