Title : Priming phosphorylation of Chk2 by polo-like kinase 3 (Plk3) mediates its full activation by ATM and a downstream checkpoint in response to DNA damage.

Pub. Date : 2006 Apr 11

PMID : 16481012






1 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 In response to ionizing radiation, Chk2 is phosphorylated on threonine 68 (T68) by ataxia-telangiectasia mutated (ATM) protein leading to its activation. Threonine checkpoint kinase 2 Homo sapiens