Title : Acetazolamide inhibits osmotic water permeability by interaction with aquaporin-1.

Pub. Date : 2006 Mar 15

PMID : 16480680






5 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Acetazolamide inhibits osmotic water permeability by interaction with aquaporin-1. Acetazolamide aquaporin 1 (Colton blood group) Homo sapiens
2 Acetazolamide, at concentrations of 1 and 10muM, inhibited the osmotic water permeability in HEK293 cells transfected with pEGFP/AQP1. Acetazolamide aquaporin 1 (Colton blood group) Homo sapiens
3 The direct binding between acetazolamide and AQP1 was detected by surface plasmon resonance. Acetazolamide aquaporin 1 (Colton blood group) Homo sapiens
4 The binding assay showed that acetazolamide could directly interact with AQP1. Acetazolamide aquaporin 1 (Colton blood group) Homo sapiens
5 This study demonstrated that acetazolamide inhibited osmotic water permeability through interaction with AQP1. Acetazolamide aquaporin 1 (Colton blood group) Homo sapiens