Title : Novel short chain fatty acids restore chloride secretion in cystic fibrosis.

Pub. Date : 2006 Mar 31

PMID : 16472777






1 Functional Relationships(s)
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1 From a panel of short chain fatty acid derivatives, we showed that 2,2-dimethyl-butyrate (ST20) and alpha-methylhydrocinnamic acid (ST7), exhibiting high oral bioavailability and sustained plasma levels, correct the DeltaF508-CFTR defect. Fatty Acids, Volatile suppressor of tumorigenicity 20 Homo sapiens