Pub. Date : 1991 Jul 1
PMID : 1646841
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Retinoic acid enhances IL-1 beta expression in myeloid leukemia cells and in human monocytes. | Tretinoin | interleukin 1 beta | Homo sapiens |
| 2 | We have examined the role of retinoic acid (RA), the biologically active metabolite of vitamin A, in expression of the IL-1 beta gene in the human myeloid leukemia cell line THP-1 and in human monocytes. | Tretinoin | interleukin 1 beta | Homo sapiens |
| 3 | We have examined the role of retinoic acid (RA), the biologically active metabolite of vitamin A, in expression of the IL-1 beta gene in the human myeloid leukemia cell line THP-1 and in human monocytes. | Tretinoin | interleukin 1 beta | Homo sapiens |
| 4 | Physiologic RA concentrations alone were not able to induce any IL-1 beta production, but they strongly enhanced the PMA-induced IL-1 beta protein production and mRNA accumulation in both human monocytes and in THP-1 cells. | Tretinoin | interleukin 1 beta | Homo sapiens |
| 5 | RA also slightly potentiated LPS-induced IL-1 beta expression in THP-1 cells but not in human monocytes. | Tretinoin | interleukin 1 beta | Homo sapiens |