Title : Comparison of several new 5-lipoxygenase inhibitors in a rat Arthus pleurisy model.

Pub. Date : 1991 Jan 25

PMID : 1646730






1 Functional Relationships(s)
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1 These results demonstrate that in this rat reverse passive Arthus pleurisy model, WY-50,295 tromethamine potently and selectively inhibits 5-lipoxygenase in vivo, and possesses a longer duration of action than the other 5-lipoxygenase inhibitors employed. Tromethamine arachidonate 5-lipoxygenase Rattus norvegicus