Pub. Date : 2006 Mar 31
PMID : 16466744
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Calcium ion exchange in crystalline gelsolin. | Calcium | gelsolin | Homo sapiens |
2 | Gelsolin is a calcium and pH-sensitive modulator of actin filament length. | Calcium | gelsolin | Homo sapiens |
3 | Here, we use X-ray crystallography to examine the extraction and exchange of calcium ions from their binding sites in different crystalline forms of the activated N and C-terminal halves of gelsolin, G1-G3 and G4-G6, respectively. | Calcium | gelsolin | Homo sapiens |
4 | However, high-resolution details of changes in the ion-binding sites may represent the initial steps toward restoration of the arrangement of domains found in the calcium-free inactive form of gelsolin in solution. | Calcium | gelsolin | Homo sapiens |
5 | Furthermore, bathing crystals with the trivalent calcium ion mimic, Tb3+, results in anomalous scattering data that permit unequivocal localization of terbium ions in each of the proposed type I and type II ion-binding sites of both halves of gelsolin. | Calcium | gelsolin | Homo sapiens |