Title : HMG-CoA reductase inhibitors reduce matrix metalloproteinase-9 activity in human varicose veins.

Pub. Date : 2005 Nov-Dec

PMID : 16465063






1 Functional Relationships(s)
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1 Simvastatin suppressed MMP-9 at both the mRNA and protein levels as well as at the urokinase-type plasminogen activator protein level, resulting in the dramatic suppression of MMP-9 activity induced by tumor necrosis factor-alpha. Simvastatin tumor necrosis factor Homo sapiens