Title : NMR studies of ligand binding to P450(eryF) provides insight into the mechanism of cooperativity.

Pub. Date : 2006 Feb 14

PMID : 16460014






1 Functional Relationships(s)
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1 The broadening and shifting observed in the 2D-{1H,15N}-HSQC-monitored titrations of 15N-Phe-labeled P450(eryF) with 9-AP and TST indicated binding on intermediate and fast chemical exchange time scales, respectively, which was consistent with the Hill-equation-derived K(S) values for these two ligands. Hydrogen cytochrome P450 family 2 subfamily B member 6 Homo sapiens