Title : The NF-kappaB-mediated control of the JNK cascade in the antagonism of programmed cell death in health and disease.

Pub. Date : 2006 May

PMID : 16456579






3 Functional Relationships(s)
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1 This participation of NF-kappaB in survival signaling often involves an antagonism of PCD triggered by TNF-R-family receptors, and is mediated through a suppression of the formation of reactive oxygen species (ROS) and a control of sustained activation of the Jun-N-terminal kinase (JNK) cascade. Reactive Oxygen Species mitogen-activated protein kinase 8 Homo sapiens
2 This participation of NF-kappaB in survival signaling often involves an antagonism of PCD triggered by TNF-R-family receptors, and is mediated through a suppression of the formation of reactive oxygen species (ROS) and a control of sustained activation of the Jun-N-terminal kinase (JNK) cascade. Reactive Oxygen Species mitogen-activated protein kinase 8 Homo sapiens
3 Effectors of this antagonistic activity of NF-kappaB on this ROS/JNK pathway have been recently identified. Reactive Oxygen Species mitogen-activated protein kinase 8 Homo sapiens