Title : Pregnancy-enhanced endothelial nitric oxide synthase (eNOS) activation in uterine artery endothelial cells shows altered sensitivity to Ca2+, U0126, and wortmannin but not LY294002--evidence that pregnancy adaptation of eNOS activation occurs at multiple levels of cell signaling.

Pub. Date : 2006 May

PMID : 16455784






2 Functional Relationships(s)
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Protein Name
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1 Expression of constitutively active Akt (ca-Akt) in UAEC resulted in slight elevation of basal eNOS activity, but relative ATP-stimulated eNOS activation was not altered by ca-Akt. Adenosine Triphosphate nitric oxide synthase 3 Homo sapiens
2 Wortmannin continued to inhibit eNOS activation by ATP in the presence of ca-Akt; LY294002 still had no inhibitory effect. Adenosine Triphosphate nitric oxide synthase 3 Homo sapiens