Title : Sulforaphane sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-resistant hepatoma cells to TRAIL-induced apoptosis through reactive oxygen species-mediated up-regulation of DR5.

Pub. Date : 2006 Feb 1

PMID : 16452234






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We also found that sulforaphane can sensitize both Bcl-xL- and Bcl-2-overexpressing hepatoma cells to TRAIL-induced apoptosis, indicating that treatment with a combination of TRAIL and sulforaphane may be a safe strategy for treating resistant hepatomas. sulforaphane BCL2 like 1 Homo sapiens