Title : Induction of nitric oxide synthase-dependent telomere shortening after functional inhibition of Hsp90 in human tumor cells.

Pub. Date : 2006 Feb

PMID : 16449656






1 Functional Relationships(s)
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1 Of particular significance, these cells exhibit a high level of nitric oxide synthase (NOS)-dependent free radical production, and simultaneous treatment of cells with the NOS inhibitor L-NAME resulted in telomere elongation and prevention of apoptosis. Free Radicals nitric oxide synthase 2 Homo sapiens