Title : Regulation of p21/ras protein expression by diallyl sulfide in DMBA induced neoplastic changes in mouse skin.

Pub. Date : 2006 Oct 8

PMID : 16448747






6 Functional Relationships(s)
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1 Regulation of p21/ras protein expression by diallyl sulfide in DMBA induced neoplastic changes in mouse skin. 6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene Harvey rat sarcoma virus oncogene Mus musculus
2 Our results showed that DAS administration leads to modulation of the DMBA-induced levels of p21/ras oncoprotein as early as 24h after the DMBA application, suggesting down-regulation of the p21/ras by DAS. 6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene Harvey rat sarcoma virus oncogene Mus musculus
3 Our results showed that DAS administration leads to modulation of the DMBA-induced levels of p21/ras oncoprotein as early as 24h after the DMBA application, suggesting down-regulation of the p21/ras by DAS. 6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene Harvey rat sarcoma virus oncogene Mus musculus
4 Our results showed that DAS administration leads to modulation of the DMBA-induced levels of p21/ras oncoprotein as early as 24h after the DMBA application, suggesting down-regulation of the p21/ras by DAS. 6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene Harvey rat sarcoma virus oncogene Mus musculus
5 Our results showed that DAS administration leads to modulation of the DMBA-induced levels of p21/ras oncoprotein as early as 24h after the DMBA application, suggesting down-regulation of the p21/ras by DAS. 6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene Harvey rat sarcoma virus oncogene Mus musculus
6 DAS administration was also found to down regulate the DMBA-induced H-ras mRNA level in mouse skin tumors. 6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene Harvey rat sarcoma virus oncogene Mus musculus