Pub. Date : 2006 Mar 10
PMID : 16446155
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Erythromycin block of the HERG K+ channel: accessibility to F656 and Y652. | Erythromycin | potassium voltage-gated channel subfamily H member 2 | Homo sapiens |
| 2 | Here we used whole-cell patch-clamp recording at 37 degrees C from heterologously expressed HERG channels in a mammalian cell line to show that erythromycin either produces a rapid open-state-dependent HERG channel inhibition, or components of both open-state-dependent and closed-state-dependent inhibition. | Erythromycin | potassium voltage-gated channel subfamily H member 2 | Homo sapiens |
| 3 | Here we used whole-cell patch-clamp recording at 37 degrees C from heterologously expressed HERG channels in a mammalian cell line to show that erythromycin either produces a rapid open-state-dependent HERG channel inhibition, or components of both open-state-dependent and closed-state-dependent inhibition. | Erythromycin | potassium voltage-gated channel subfamily H member 2 | Homo sapiens |