Title : Identification of human liver cytochrome P450 enzymes responsible for the metabolism of lonafarnib (Sarasar).

Pub. Date : 2006 Apr

PMID : 16443667






1 Functional Relationships(s)
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1 There was a high correlation between the formation of M1, determined in 10 human liver microsomal samples, and 6beta-hydroxylation of testosterone catalyzed by CYP3A4/5 (r = 0.93). Testosterone cytochrome P450 family 3 subfamily A member 4 Homo sapiens