Pub. Date : 2005 Dec
PMID : 16441976
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Lactate and H(+) are suggested to promote the sickling process in red blood cells (RBCs) containing hemoglobin S. We demonstrated greater activity of the RBC monocarboxylate cotransporter MCT-1, lower RBC deformability and impaired hematological indices in sickle cell trait (SCT) carriers compared to control subjects, suggesting an involvement of MCT-1 in hemorheological disturbances in SCT carriers. | Lactic Acid | solute carrier family 16 member 1 | Homo sapiens |
2 | Lactate and H(+) are suggested to promote the sickling process in red blood cells (RBCs) containing hemoglobin S. We demonstrated greater activity of the RBC monocarboxylate cotransporter MCT-1, lower RBC deformability and impaired hematological indices in sickle cell trait (SCT) carriers compared to control subjects, suggesting an involvement of MCT-1 in hemorheological disturbances in SCT carriers. | Lactic Acid | solute carrier family 16 member 1 | Homo sapiens |