Pub. Date : 2006 May
PMID : 16437585
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Inhibition of the enzyme catechol-O-methyl transferase (COMT) by entacapone extends the half-life of levodopa and minimizes variability in plasma levodopa levels. | entacapone | catechol-O-methyltransferase | Rattus norvegicus |
| 2 | Inhibition of the enzyme catechol-O-methyl transferase (COMT) by entacapone extends the half-life of levodopa and minimizes variability in plasma levodopa levels. | entacapone | catechol-O-methyltransferase | Rattus norvegicus |
| 3 | The aim of the present study was to characterize the effect of the early administration of the COMT inhibitor entacapone in the recently described model of LIDs in rats with a nigrostriatal lesion induced by 6-hydroxydopamine (6-OHDA). | entacapone | catechol-O-methyltransferase | Rattus norvegicus |